Artemisinin-based combination therapies are the gold standard treatment for uncomplicated malaria. A seminal study by Paddon . detailed an efficient approach for producing artemisinic acid from engineered yeast and its conversion to artemisinin, and demonstrated how to use metabolic engineering and synthetic biology for the production of bioactive compounds.
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- Source: https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(22)00315-8?rss=yes