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[Mirror] Quadratic Arithmetic Programs: from Zero to Hero

Vitalik Buterin via the Vitalik Buterin Blog This is a mirror of the post at https://medium.com/@VitalikButerin/quadratic-arithmetic-programs-from-zero-to-hero-f6d558cea649 There has been a lot of interest lately in the technology behind zk-SNARKs, and people are increasingly trying to demystify something that many have come to call "moon math" due to its perceived sheer indecipherable complexity. zk-SNARKs are indeed quite challenging to grasp, especially due to the sheer number of moving parts that need to come together for the whole thing to work, but if we break the technology down piece by piece then

Coya Therapeutics Reports Additional Biomarker and Imaging Data Showing Decrease in Neuroinflammation with COYA 301 in Alzheimer’s Disease.

Highlights Coya reports new data illustrating that administration of COYA 301 (low dose Interleukin-2 (IL-2)) in an open- label study in 8 patients with mild to moderate AD (COYA 301 Trial) resulted in a statistically significant reduction in the expression of three well characterized proinflammatory cytokines -- Tumor Necrosis Factor alpha (TNF-α), Interleukin 6 (IL-6), and Interleukin 1- Beta (IL-1β) -- which correlated with lack of cognitive decline of the patients over the course of the study. TNF-α is one of the main inflammatory cytokines involved in initiating and propagating

Press Release: TP ICAP announces first live trade through Fusion Digital Assets with GMEX trading and post-trade technology

Fusion Digital Assets – TP ICAP’s wholesale marketplace for spot cryptoassets – is now live and has successfully completed its first XBTUSD pairs trade with the associated settlement processed by Fidelity Digital Assets℠ London, New York, 24 May 2023: GMEX Technologies (“GMEX”), a subsidiary of GMEX Group, a leader in digital business and technology solutions for capital markets players, exchanges and post-trade market infrastructure, today announced that TP ICAP, the world’s largest interdealer broker, has gone live with its Fusion Digital Assets wholesale cryptoasset exchange, powered by GMEX trading and post trade technology.